How DNA methylation affects gene expression
DNA methylation serves as a pivotal epigenetic mechanism that significantly influences gene regulation by recruiting proteins that facilitate gene repression or by hindering transcription factors from...
View ArticleRedefining 5hmC: more than just a stepping stone in the DNA demethylation...
An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene...
View ArticleHow liquid biopsy is transforming neurodegenerative disease diagnosis
Neurodegenerative diseases pose significant challenges in diagnosis and treatment, affecting millions worldwide. These conditions, including Alzheimer’s disease, cause progressive deterioration of the...
View ArticleWhat is epigenetics? A brief introduction into how & why our genes switch on...
Passed from parents to offspring and containing information that will be used to specify physical and biological characteristics, genes are specific sequences within DNA that are responsible for...
View ArticlecfDNA fragmentomics: the next frontier in genetic testing
Cell-free DNA (cfDNA) has emerged as a groundbreaking tool in genetic testing, offering a non-invasive window into the human genome. This circulating DNA, released by cells into the bloodstream,...
View Articlebiomodal to present new 6-base genome data showing enhanced sensitivity for...
CAMBRIDGE, England. biomodal, an omics-based life sciences technology and analytics company, today announced it will present new data highlighting the utility of duet multiomics solution evoC in the...
View ArticleHow histone modifications impact gene regulation
Histones are fundamental proteins that play a crucial role in the organisation and regulation of DNA within eukaryotic cells. These highly conserved proteins are abundant in lysine and arginine...
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Multiomic 6-base data from cell-free DNA enhances the performance of liquid...
Download this poster Credits Fabio Puddu¹Annelie Johansson¹Aurélie Modat¹Jamie Scotcher¹Riccha Sethi¹Shirong Yu¹ ²Nick Harding¹Mark S. Hill¹Ermira Lleshi¹Casper Lumby¹Jean Teyssandier¹Michael Wilson¹...
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Simultaneous single cell sequencing of genetic and epigenetic bases
Download this poster Credits Aldo Ciau-UitzChenfu ShiIris ValentJack M MonahanJinfeng ChenJulia VivianMinna TaipalePáidí CreedPaula GolderPaula Kokko-GonzalesRafael TavaresShankar...
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Inferring genome organisation and gene regulation from 6-base sequencing data
Download this poster Credits Fabio Puddu¹Annelie Johansson¹Aurélie Modat¹Jamie Scotcher¹Riccha Sethi¹Shirong Yu¹ ²Nick Harding¹Mark S. Hill¹Ermira Lleshi¹Casper Lumby¹Jean Teyssandier¹Michael Wilson¹...
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