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Removal of end-repair from liquid biopsy library preparation reduces...
Credits Luke Sarre¹ Aurelie Modat¹ Lidia Prieto-Lafuente¹ Tom Charlesworth¹ Angela Simeone¹ Mike Stubbington¹ 1 biomodal Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK Download...
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Integrated 6-base cfDNA profiling reveals complementary genetic, epigenetic...
Credits Fabio Puddu¹ Annelie Johansson¹ Angela Simeone¹ Mike Stubbington¹ 1 biomodal Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK Download the poster 1. Introduction Cell-free...
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Fragment-level integration of epigenetic and genetic signals for...
Credits Aurélie Modat¹ Luke Sarre¹ Cillian Nolan¹ Annelie Johansson¹ Fabio Puddu¹ Angela Simeone¹ Rob Crawford¹ Mike Stubbington¹ Rob Osborne¹ 1 biomodal Ltd, The Trinity Building, Chesterford...
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The 6- base genome reveals novel 5mC and 5hmC biomarkers enabling the...
Credits Mark Consugar¹Annelie Joahnsson¹Aurelie Modat¹Rebecca Elwood¹Tom Charlesworth¹Angela Simeone¹Mike Stubbington¹Robert J Osborne¹Maria Starvaggi Cucuzza¹˒²˒³Maria Needhamsen¹˒²Maja Jagodic¹˒²˒³1...
View ArticleAdvancing Neurological Liquid Biopsy via Six-Base Sequencing of Cerebrospinal...
Real-time molecular insights into the human brain are crucial for understanding 44 neurological conditions and development of soluble biomarkers but challenged by the 45 limited access to target...
View ArticleAdvancing Neurological Liquid Biopsy via Six-Base Sequencing of Cerebrospinal...
Given the difficulty of tissue sampling the use of circulating biomarkers in neurology is a growing field. Recent diagnostic approaches that use circulating protein biomarkers, such as neurofilament...
View Articlebiomodal Launches duet mosaic Giving Liquid Biopsy Researchers and Developers...
The duet mosaic family leverages a single-stranded ligation technology to resolve genetics, epigenetics and fragmentomics from the same cfDNA molecule in a streamlined, automation-ready workflow so...
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6-base multi-modal data is a powerful liquid biopsy platform for cancer...
Credits Fabio PudduAnnelie JohanssonCillian NolanRobert BlanshardEdyta Bocian-CanepaTom CharlesworthAngela SimeoneMike Stubbingtonbiomodal Ltd, The Trinity Building, Chesterford Research Park,...
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Single stranded ligation enhances the performance of the duet evoC 6- base...
Credits Tom CharlesworthErmira LleshiRobert CrawfordAurelie ModatLidia Prieto-LafuenteEdyta Bocian-CanepaJens FullgrabeEleni PahitaRebecca EllwoodMengjie LiMarjana LilaBrett EvanRobert Osbornebiomodal...
View ArticleUnderstanding the Value of DNA Methylation Data
From global methylation patterns to differentially methylated regions, high-resolution data can help you get more from your studies. Among the most studied epigenetic marks are 5-methylcytosine (5mC)...
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Integrative Dual ctDNA 5mC/5hmC Methylomics and Clonal Reconstruction...
Download this poster Credits Chennan Li, Anna Baj Clara C. Y. Seo Nicholas T. Terrigino John R. Bright S. Thomas Hennigan Isaiah M. King Scott Wilkinson Tzu-Ting Huang Shana Y. Trostel William D. Figg...
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Single stranded ligation enhances the performance of the duet evoC 6-base...
Download this poster Credits Aurelie Modat Luke Sarre Robert Blanshard Chris Renders Lisabet Andreasen Fabio Puddu Tom Charlesworth Robert Osborne Thao Hunyh Robert Crawford biomodal Ltd, The Trinity...
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The importance of high analytical sensitivity and specificity of 5 and 6-base...
Download this poster Credits Aurelie Modat Luke Sarre Robert Blanshard Chris Renders Lisabet Andreasen Fabio Puddu Tom Charlesworth Robert Osborne Thao Hunyh Robert Crawford biomodal Ltd, The Trinity...
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Simultaneous identification of methylation and somatic variants can improve...
Download this poster Credits Aurelie ModatCillian NolanErmira LleshiRobert BlanshardSascha SeidelFabio PudduAnnelie JohanssonErmira LleshiRobert CrawfordTom CharlesworthRobert J Osbornebiomodal Ltd,...
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Using the 6-base genome for full multiomic analysis of cfDNA through combined...
Download this poster Credits Mark Consugar Fabio Puddu Thao Huynh Fabio Puddu Annelie Johansson Ermira Lleshi Robert Crawford Tom Charlesworth Steven Ciaramaglia Robert J Osborne biomodal Ltd, The...
View ArticleFor Methylation Sequencing, The Cancer Is In The Details
Colorectal cancer (CRC) is a disease of subtle progression and devastating impact. Years may elapse as small nodes of stage I disease grow into diffuse metastatic networks. With each step in its...
View ArticleNational Cancer Institute researchers show 6-base sequencing has the...
Liquid biopsies can detect actionable mutations and infer broad tumour states from genome-wide cfDNA measurements, but quantitative transcriptome-like phenotyping at single gene resolution still...
View ArticleResearchers at Johns Hopkins use duet evoC to reveal genetic and epigenetic...
Researchers at Johns Hopkins University investigated how genetic and epigenetic regulation combine to control gene expression in catastrophic antiphospholipid syndrome (CAPS), a rare but severe...
View ArticleThe importance of 5mC and 5hmC for biomarker discovery and biological insight...
The integration of genetic and epigenetic information is essential for a comprehensive understanding of genome function and regulation. Traditional sequencing methods often fall short in capturing...
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biomodal and Element Biosciences Combine Duet Multiomic and High-Throughput...
CAMBRIDGE, England and SAN DIEGO—February 23, 2026—biomodal, an omics-based life sciences technology and analytics company, today announced at the AGBT 2026 General Meeting that biomodal’s duet...
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