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Multiomic 6-base sequencing of cell-free DNA improves liquid biopsy classifiers
Download this poster Credits Robert J Osborne¹Fabio Puddu¹, Annelie Johansson¹Aurélie Modat¹Jamie Scotcher¹Riccha Sethi¹Shirong Yu¹ ²Nick Harding¹Mark Hill¹Ermira Lleshi¹Casper Lumby¹Jean...
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A high-performance toolkit for large-scale analysis of 5- and 6-base genomes
Download this poster Credits Jean TeyssandierNicholas HardingSabri JamalMichael J. WilsonGary FrewinNicola WongWilliam StarkMark S. HillPáidí Creed 1. Introduction We present a computational toolkit...
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OGT prevents DNA demethylation and suppresses the expression of transposable...
Download this poster Credits Robert Crawford¹ Hugo Sepulveda Xiang Li Leo J. Arteaga-Vazquez Isaac F. López-Moyado Melina Brunelli Lot Hernandez Espinosa Xiaojing Yue J. Carlos Angel Caitlin Brown...
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Multiomic 6-base sequencing enhances the performance of early colorectal...
Download this poster Credits Fabio Puddu¹Annelie Johansson¹Aurélie Modat¹Jamie Scotcher¹Riccha Sethi¹Nick Harding¹Mark Hill¹Ermira Lleshi¹Casper Lumby¹Jean Teyssandier¹Michael Wilson¹Robert...
View ArticleThe ‘six-base genome’ sheds light on hidden cancer dynamics
Tracking cancer epigenetics While early liquid biopsy research efforts focused on detecting DNA sequence changes, the importance of epigenetics has recently come to the fore, says Sarah-Jane Dawson, a...
View ArticleFeatured preprint: epigenome-wide DNA methylation association study
Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation Within the Division of Genetic Medicine at Vanderbilt University Medical Center, Associate...
View ArticleFeatured preprint: understanding the relationship between DNA methylation and...
Temporally discordant chromatin accessibility and DNA demethylation define short and long-term enhancer regulation during cell fate specification Research at Assistant Professor Emily Hodges’ lab at...
View ArticleOGT prevents DNA demethylation and suppresses the expression of transposable...
Research paper shows 6-base sequencing can reveal early biomarkers of genome dysfunction that lead to diseases Exciting news, Professor Anjana Rao’s Lab at La Jolla Institute for Immunology has...
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Assessment of ctDNA detection in localised prostate cancer using a multiomics...
Download this poster Credits Hanieh Sadeghi1 Johannes Mischinger2Raul Alejandro Mejia Pedroza1Ellen Heitzer1,3,4 Institute of Human Genetics, Diagnostic and Research Center for Molecular Biomedicine...
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Buried Threats: DNA Methylation, Transposable Elements, and the Hidden...
The remnants of ancient viral infections are littered across the human genome. Many of these relics, known as transposable elements (TE), are believed to have brought cryptic promoters, enhancers, and...
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